Research shows distinct targeting of excitatory and inhibitory projections in the brain, suggesting an organizational structure influencing visual processing.
• GABAergic IC neurons target both superficial and deeper layers of the SC (SC.sup and SC.deep) with some preference to SC.sup. • Glutamatergic IC neurons preferentially target SC.deep. • Ratio of GABAergic neurons in SC.sup projection is higher than SC.deep and canonical IC-MGB projections. • Rostral shell areas of the IC are important for, especially inhibitory, projection to the SC.
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Saqib et al. (2026) studied this question.
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