Why the study?
Long-term health consequences of SARS-CoV-2 infection remain incompletely identified, presenting major challenges in symptom interpretation and management in patients with comorbidities like neoplastic disease.
Does thiethylperazine maleate combined with nonpharmacological measures improve dizziness and nausea in a patient with orthostatic hypotonia post-SARS-CoV-2 infection?
Does thiethylperazine maleate combined with nonpharmacological measures improve dizziness and nausea in a patient with orthostatic hypotonia post-SARS-CoV-2 infection?
Simple pharmacological and nonpharmacological measures can provide sustained symptom control for orthostatic hypotonia occurring as a late sequela of SARS-CoV-2 infection.
May support symptom control in post-COVID orthostatic hypotonia; leaves open efficacy pending controlled trials.
BACKGROUND: The SARS-CoV-2 pandemic has become a challenge for the entire healthcare system. Treatment for COVID-19 includes casual and symptomatic management in the acute phase of the disease and focuses on the treating early complications of the disease. Long-term health consequences of the infection have not yet been fully identified. A special group of patients with comorbidities, including neoplastic disease for whom the interpretation and management of symptoms is a major challenge. CASE PRESENTATION: In this case report, we present a 73-year-old woman with recently diagnosed gastric adenocarcinoma in whom we diagnosed orthostatic hypotonia in the aftermath of SARS-CoV-2 infection. We administered thiethylperazine maleate 6.5 mg daily. Additionally, we advised the patient to slowly lift from the recumbent position, raise the headboard, take meals in small portions, and increase fluid intake. These pharmacological and nonpharmacological measures resulted in sustained relief of dizziness and nausea. CONCLUSIONS: The occurrence of orthostatic hypotonia seems a possible late sequela of SARS-CoV-2 infection, and simple measures appeared sufficient to achieve sustained symptom control.
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Kluczna et al. (2022) studied this question.
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