Why the study?
Cardiac syncope carries a higher risk of mortality than non-cardiac causes, but brain natriuretic peptide has not been thoroughly evaluated in patients with syncope.
Does the assessment of BNP and NT-pro-BNP help in diagnosing cardiac syncope in patients presenting to emergency departments?
Does the assessment of BNP and NT-pro-BNP help in diagnosing cardiac syncope in patients presenting to emergency departments?
This narrative review summarizes the potential role of BNP and NT-pro-BNP as biomarkers for differentiating cardiac from non-cardiac syncope in the emergency department.
May aid ED differentiation of cardiac syncope; leaves open need for prospective validation before clinical adoption.
Cardiac disease is the second common cause of syncope in emergency departments. Patients with Cardiac syncope have a higher risk of mortality than those who have a non-cardiac problem. Brain natriuretic peptide (BNP) as a cardiac marker has not thoroughly been evaluated in patients with syncope. This article focuses on the studies that have assessed BNP and NT-pro-BNP in cardiac and non-cardiac syncope patients in emergency departments.
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Disfani et al. (2018) studied this question.
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