Advances in flexible and wearable pH sensors for wound healing monitoring

Wound healing has been recognized as a complex and dynamic regeneration process and attracted increasing interests on its management. For effective wound healing management, a continuous monitoring on the wound healing based on sensors is essential. Since pH has been found to play an important role on wound healing process, a variety of pH sensors systems for wound healing monitoring have been greatly developed in recent years. Among these pH sensors, flexible and wearable pH sensors which can be incorporated with wound dressing have gained much attention. In this review, the recent advances in the development of flexible and wearable pH sensors for wound healing monitoring have been comprehensive summarized from the range of optical and electrochemical bases.