Why the study?
Does adiponectin modulate endothelial inflammatory response and are its levels associated with coronary artery disease?
Does adiponectin modulate endothelial inflammatory response and are its levels associated with coronary artery disease?
Adiponectin inhibits endothelial inflammatory responses in vitro and is found at lower levels in patients with coronary artery disease, suggesting it may serve as a biomarker for CAD risk and a protective factor against vascular disease.
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Should not yet change CAD risk assessment; leaves open adiponectin's role in endothelial inflammation.
Ouchi et al. (1999) studied this question.
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