The case of a 57-year-old woman with the diagnosis of angioimmunoblastic lymphadenopathy (AILD) is reported. During the 15 years of the disease, no malignant transformation had been detected. The clinical picture is unusual in certain respects. Lymph node manifestation had been preceded by extraglandular AILD infiltrates. All histologic materials showed a picture typical of AILD. A functional study of peripheral lymphocyte subpopulations revealed decreased natural cytotoxicity and decreased T-lymphocyte activity.
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Garam et al. (1981) studied this question.
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