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November 26, 2013Infection and ImmunityOpen Access

Toxoplasma gondii Inhibits Gamma Interferon (IFN-γ)- and IFN-β-Induced Host Cell STAT1 Transcriptional Activity by Increasing the Association of STAT1 with DNA

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Authors

EREmily E. RosowskiClemson UniversityQNQuynh NguyenUniversity of PennsylvaniaACAna Camejoi3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto

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Rosowski et al. (2013) studied this question.

synapsesocial.com/papers/6a1d758d266863fda62f4f2chttps://doi.org/10.1128/iai.01291-13
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins1994 · 6,160 citations
  2. 2IFN regulatory factor-1 plays a central role in the regulation of the expression of class I and II MHC genes in vivo1997 · 164 citations
  3. 3Impaired Chromatin Remodelling at STAT1-Regulated Promoters Leads to Global Unresponsiveness of Toxoplasma gondii-Infected Macrophages to IFN-γ2012 · 85 citations