Key result
Cardiac troponins and high-sensitive assays allow prompt identification of acute coronary syndromes, earlier discharge for nonischemic chest pain, and offer broad prognostic value.
Cardiac troponins, particularly high-sensitivity assays, are highly valuable biomarkers for diagnosing acute coronary syndromes and providing prognostic information across various cardiac and noncardiac conditions.
May support troponin-guided ACS evaluation and discharge; leaves optimal assay thresholds and protocols open for prospective validation.
The use of biomarkers in a variety of conditions is aimed at rapid and precise diagnosis leading to timely treatment. The evolution of cardiac troponins and more recently high sensitive troponin assays allows both prompt identification of ACS and earlier discharge of nonischemic chest pain patients. Moreover, there is increasing evidence of prognostic importance of troponins in nonischemic cardiac conditions such as heart failure and AF as in noncardiac conditions such as sepsis and COPD and more recently in the general healthy population. With the increasing scientific data backing troponins, it is the best contemporary available assay closest to " the ideal biomarker ".
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Das et al. (2017) conducted a review in Various conditions including acute coronary syndromes, heart failure, and sepsis. Cardiac troponins was evaluated. Cardiac troponins and high-sensitive assays allow prompt identification of acute coronary syndromes, earlier discharge for nonischemic chest pain, and offer broad prognostic value.
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