March 28, 2019Circulation Research110 citationsOpen Access
View Full PaperBlood Pressure Measurement and Treatment Decisions
Key Result
Masked hypertension is associated with increased risk of target organ damage and cardiovascular events, whereas cardiovascular risk in white-coat hypertension depends on coexisting risk factors.
Structured PICO
P
Population
Patients with white-coat and masked hypertension
I
Intervention
Out-of-office blood pressure measurement and antihypertensive treatment
This review highlights the importance of out-of-office blood pressure measurement for diagnosing white-coat and masked hypertension and notes the unmet need for robust data to guide their treatment.
Limitations
- Lack of robust data to support recommendations around the use of antihypertensive treatment for the management of white-coat and masked hypertension
Abstract
White-coat and masked hypertension are important hypertension phenotypes. Out-of-office blood pressure measurement is essential for the accurate diagnosis and monitoring of these conditions. This review summarizes literature related to the detection and diagnosis, prevalence, epidemiology, prognosis, and treatment of white-coat and masked hypertension. Cardiovascular risk in white-coat hypertension appears to be dependent on the presence of coexisting risk factors, whereas patients with masked hypertension are at increased risk of target organ damage and cardiovascular events. There is an unmet need for robust data to support recommendations around the use of antihypertensive treatment for the management of white-coat and masked hypertension.