Young Black adults exhibited higher nighttime diastolic blood pressure (63 vs 58 mmHg) and attenuated blood pressure dipping compared with White adults, which was associated with greater neighborhood deprivation.
Cross-Sectional (n=47)
No
Does neighborhood deprivation and Black race associate with higher nighttime blood pressure and attenuated blood pressure dipping in young adults?
Neighborhood deprivation is associated with attenuated nighttime blood pressure dipping in young adults, which may partially explain racial disparities in cardiovascular disease risk.
Tasa de eventos absoluta: 63% vs 58%
valor p: p=0.003
Abstract Background Ambulatory blood pressure ( BP ) monitoring measures nighttime BP and BP dipping, which are superior to in-clinic BP for predicting cardiovascular disease ( CVD ), the leading cause of death in America. Compared with other racial/ethnic groups, Black Americans exhibit elevated nighttime BP and attenuated BP dipping, including in young adulthood. Social determinants of health contribute to disparities in CVD risk, but the contribution of neighborhood deprivation on nighttime BP is unclear. Therefore, we examined associations between neighborhood deprivation with nighttime BP and BP dipping in young Black and White adults. Methods We recruited 21 Black and 26 White participants (20 M/27 F, mean age: 21 years, body mass index: 25±4 kg/m 2 ) for 24-hour ambulatory BP monitoring. We assessed nighttime BP and BP dipping (nighttime:daytime BP ratio). The area deprivation index ( ADI ) was used to measure neighborhood deprivation. Associations between ADI and ambulatory BP were examined. Results Black participants exhibited higher nighttime diastolic BP compared with White participants (63±8 mmHg vs 58±7 mmHg, p =0.003), and attenuated BP dipping ratios for both systolic (0.92±0.06 vs 0.86±0.05, p =0.001) and diastolic BP (0.86±0.09 vs 0.78±0.08, p =0.007). Black participants experienced greater neighborhood deprivation compared with White participants (ADI scores: 110±8 vs 97±21, p <0.001), and ADI was associated with attenuated systolic BP dipping (ρ=0.342, p =0.019). Conclusions Our findings suggest neighborhood deprivation may contribute to higher nighttime BP and attenuated BP dipping, which are prognostic of CVD, and more prevalent in Black adults. Targeted interventions to mitigate the effects of neighborhood deprivation may help to improve nighttime BP. Clinical Trial Registry URL: https://www.clinicaltrials.gov ; Unique identifier: NCT04576338 Clinical Perspective We demonstrate young Black adults exhibit higher nighttime blood pressure and attenuated nighttime blood pressure dipping compared with young White adults. Black adults were exposed to greater neighborhood deprivation, which was associated with attenuated blood pressure dipping, irrespective of race. Our findings add to a growing body of literature indicating neighborhood deprivation may contribute to increased cardiovascular disease risk.
Jeong et al. (Tue,) conducted a cross-sectional in Ambulatory blood pressure (n=47). Black race vs. White race was evaluated on Nighttime diastolic blood pressure (mmHg) (p=0.003). Young Black adults exhibited higher nighttime diastolic blood pressure (63 vs 58 mmHg) and attenuated blood pressure dipping compared with White adults, which was associated with greater neighborhood deprivation.