Why the study?
Does intravenous 7E3-F(ab')2 inhibit platelet function in patients with unstable angina pectoris?
Population
16 patients with unstable angina pectoris
Design
Cohort
Follow-up
72 hours
Authors
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Supports platelet inhibition with 7E3-F(ab')2 in unstable angina without spontaneous bleeding; hypothesis-generating for clinical outcomes.
Does intravenous 7E3-F(ab')2 inhibit platelet function in patients with unstable angina pectoris?
Intravenous 7E3-F(ab')2 induces dose-related, profound inhibition of platelet aggregation and prolongation of bleeding time without causing spontaneous bleeding in patients with unstable angina.
Gold et al. (1990) studied this question.
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