Why the study?
Most knowledge on androgen abuse and adverse cardiovascular changes relies on cross-sectional studies sensitive to bias, leaving the magnitude and reversibility of these effects unclear.
Does androgen abuse cause adverse changes in blood pressure, lipid metabolism, and erythrocytosis in male amateur strength athletes?
Population
100 men (≥18 years) performing an androgen cycle
Comparison
During androgen cycle vs baseline, 3 months post-cycle, and 1 year post-start
Design
Prospective cohort study
Follow-up
1 year after start of the cycle
Authors
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Androgen abuse was associated with reversible BP and lipid shifts; leaves open long-term CV risk in strength athletes.
Does androgen abuse cause adverse changes in blood pressure, lipid metabolism, and erythrocytosis in male amateur strength athletes?
Androgen abuse causes small but clinically relevant, rapidly reversible adverse changes in blood pressure, lipid metabolism, and erythrocytosis.
Smit et al. (2022) studied this question.
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