Why the study?
Does downhill walking (eccentric contractions) cause a larger delayed rise in plasma creatine kinase compared to uphill walking (concentric contractions) in normal subjects?
Population
5 normal subjects
Comparison
Downhill walking on a treadmill inclined at 13… vs Uphill walking on a treadmill inclined at 13…
Design
Other
Follow-up
4-7 days
Authors
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May warrant caution interpreting delayed CK after eccentric activity; leaves open clinical thresholds and generalizability.
Does downhill walking (eccentric contractions) cause a larger delayed rise in plasma creatine kinase compared to uphill walking (concentric contractions) in normal subjects?
Eccentric contractions, such as those during downhill walking, are responsible for large delayed efflux of creatine kinase.
Newham et al. (1986) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: