Why the study?
Although aspirin and clopidogrel reduce colorectal cancer risk, their effects on gastric cancer remain under investigation, prompting an evaluation of clopidogrel on gastric precancerous lesions.
Does clopidogrel, low-dose aspirin, or non-aspirin NSAID use have a chemopreventive effect on the development of gastric precancerous lesions?
Does clopidogrel, low-dose aspirin, or non-aspirin NSAID use have a chemopreventive effect on the development of gastric precancerous lesions?
Clopidogrel, low-dose aspirin, and non-aspirin NSAIDs do not appear to prevent gastric precancerous lesions but are associated with a significantly increased risk of severe gastroduodenal lesions such as peptic ulcers.
Associated with higher peptic ulcer incidence without reducing intestinal metaplasia; leaves open chemopreventive effects on gastric precancerous lesions.
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Taner Akyol (2023) studied this question.
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