A comprehensive quality control system for Chinese herbal medicine based on HPLC ratio quantitative fingerprinting and spectral quantized fingerprinting combined with antioxidant activity: A case of Siegesbeckiae Herba

< 128.3 %). Finally, the fingerprint-efficacy correlation analysis was employed to identify potential antioxidant components in SH, including chlorogenic acid, caffeic acid, and rutin. The integrated evaluation method developed in this study enables comprehensive and rapid quality assessment of SHs through chromatographic fingerprinting, spectroscopic profiling, precise quantification, and antioxidant activity, thereby providing a novel and feasible strategy for quality control of CHMs and their preparations.