A computer library of the literature on anti-motionsickness drugs has been established at the Navy Institute of Aerospace Medicine at Pensacola, Fla. The overall effectiveness of the antihistamines was 70.6%; for the belladonnas it was 50.1%, and for the phenothiazines, 44.9%. The overall results of British studies indicated a greater effectiveness for the belladonnas than for the antihistamines, which is the reverse of the results of US studies. In a recent series of studies dextroamphetamine was found to be a highly effective anti-motion-sickness drug with an overall effectiveness of 64%. The drugs were found to be more effective for motion sickness during flight than for motion sickness at sea.
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Charles D. Wood (1966) studied this question.