Why the study?
Are plasma 5-HIAA concentrations elevated in subjects with metabolic syndrome compared to those without?
Population
311 subjects (152 men and 159 women) recruited from a clinic providing regular health check-ups
Design
Cross-sectional
Authors
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Higher 5-HIAA in MetS should not yet change practice; leaves open serotonin's role in cardiometabolic risk.
Are plasma 5-HIAA concentrations elevated in subjects with metabolic syndrome compared to those without?
Plasma 5-HIAA concentrations are elevated in subjects with metabolic syndrome and correlate with metabolic parameters, suggesting a potential role of serotonin in cardiovascular disease development in this population.
Fukui et al. (2011) studied this question.
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