Why the study?
It has been argued that wave and Windkessel phenomena cannot be considered simultaneously, and traditional impedance analysis had unresolved implications.
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Design
Review
Subtracting the Windkessel component from measured aortic pressure clarifies wave propagation and reflection patterns, addressing limitations of traditional impedance analysis.
Some have said that it is inappropriate and perhaps impossible to consider wave and Windkessel phenomena simultaneously. For 50 years, arterial hemodynamics has been dominated by the frequency-domain “impedance analysis” in which it was assumed that all variations in aortic pressure and flow were caused only by forward- and backward-going waves. This paper is a review of the results of incorporating the effects of Frank’s Windkessel. We have taken the view that measured aortic pressure is the sum of a Windkessel component and forward-going and backward-going wave components. When the Windkessel component is initially subtracted out, the pattern of propagation and reflection of wave components becomes clear. Furthermore, this analysis obviates the implications of impedance analysis that have not been explained satisfactorily.
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John V. Tyberg (2021) studied this question.
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