This study aims to explain the mechanism by which overall cardiac systolic function remains normal in genetic asymmetric septal hypertrophy despite a hypocontractile ventricular septum.
May clarify compensatory mechanisms preserving systolic function in genetic ASH; leaves open any clinical implications pending prospective validation.
Genetic asymmetric septal hypertrophy is a primary myocardial disease with characteristic echocardiographic features. Echocardiographic studies in patients have shown that the ventricular septum is a hypocontractile structure. Since overall cardiac systolic function in this disease is normal, the present study was undertaken to explain this phenomenon.
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Cate et al. (1977) studied this question.
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