Viruses and genetics in pregnancy and birth

In this study we presented several patients with genital infections during pregnancy, perinatal infection, de novo genetics syndromes, sterility problems and spontaneous abortions with HSV1, HSV2, CMV, Adeno, Parvo B19, RSV, EBV and Coxsackie virus. Spontaneous abortion were provoked (or at least associated) with viral infection. For some we had expected such pregnancy outcomes, and for some we observed chromosome breaks that by repetitive screening, after cessation of acute viral infection, could no longer been seen. Nonspecific chromosomal aberrations were associated with HSV type 2, herpes zoster and Ebstein Barr virus infection. EBV is a causative agent of autoimmune entities were polyclonality in serological findings is present, we are searching for the same answer in the cause of spontaneous abortion with or without chromosomes abnormalities with atypical serology values of those viruses at both partners.