A comparison of various measures of association for 2 x 2 data was carried out by computer analysis. Bivariate normal population distributions of known p were generated and divided into quadrants, yielding a total of 1,539 2 x 2 tables. For each of these tables, 14 measures of association were calculated and evaluated against the underlying p. A recently developed measure of association based on the odds-ratio (Chambers, 1982) appeared to be the most accurate in capturing the p underlying a majority of 2×2 tables. The phi coefficient, despite its continuing popularity, was found to be relatively inaccurate under most conditions studied.
No takes yet. Share an insight, caveat, or question.
Alexander et al. (1985) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: