Scaling Out by Microwave‐Assisted, Continuous Flow Organic Synthesis (MACOS): Multi‐Gram Synthesis of Bromo‐ and Fluoro‐benzofused Sultams Benzthiaoxazepine‐1,1‐dioxides

Go with the flow! Using a combination of continuous-flow techniques and microwave irradiation, a 19-member collection of 5–10 gram quantities of benzthiaoxazepine-1,1-dioxides has been produced (see scheme). The elimination of intermediate- and large-scale process optimization by invoking the concept of scale-out (rather than scale up) has significantly reduced the time necessary to prepare these compounds. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.