What is the clinical evidence from this study?

Study design: Cohort. Population: Ischemic stroke (n=249537). Intervention: Greenness exposure (NDVI/EVI) vs. Lower greenness exposure. Primary outcome: All-cause mortality (16.9% decreased risk).

What does this research mean for the field?

Increased greenness exposure is associated with reduced mortality risk among ischemic stroke patients, with each interquartile range increase in contemporaneous NDVI reducing all-cause mortality by 16.9%, an effect enhanced in regions with high air pollution. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

October 31, 2025BMC Public HealthOpen Access

Bidirectional effect modification of greenness exposure and air pollution on ischemic stroke mortality across different temporal scales

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Key result

Higher residential greenness linked to ~17% lower all-cause mortality after ischemic stroke.

16.9% decreased risk
n=249,537

Why the study?

Does greenness exposure reduce mortality in ischemic stroke patients?

Population

249,537 ischemic stroke (IS) patients from Shandong Province, China (2013-2019)

Comparison

Greenness exposure vs Lower levels of greenness exposure

Design

Cohort

Follow-up

2013-2019

Authors

BZBingyin ZhangYuncheng University QCQiyong CaoBengbu Medical College QZQiongqi ZhangBengbu Medical College

Discussion

Member takes

Implication

Greenness exposure significantly reduces all-cause, cardiovascular, and stroke mortality in ischemic stroke patients, with enhanced protective effects in areas with high air pollution.

Study Design

Type

Cohort (n=249,537)

Structured PICO

Does greenness exposure reduce mortality in ischemic stroke patients?

Population

249,537 ischemic stroke patients from Shandong Province, China, evaluated between 2013 and 2019 to assess the association between greenness exposure and mortality.

Exposure

Greenness exposure (cumulative and contemporaneous NDVI/EVI)

Comparator

Lower levels of greenness exposure

Outcome

All-cause, cardiovascular, and stroke mortalityhard clinical

Main Result

Effect estimate: 16.9% decreased risk

Greenness exposure significantly reduces all-cause, cardiovascular, and stroke mortality in ischemic stroke patients, with enhanced protective effects in areas with high air pollution.

Limitations

spatial resolution variability in exposure assessments

Cite This Study

Zhang et al. (2025) conducted a cohort in Ischemic stroke (n=249,537). Greenness exposure (NDVI/EVI) vs. Lower greenness exposure was evaluated on All-cause mortality (16.9% decreased risk). Each interquartile range increase in contemporaneous greenness exposure (NDVI) was associated with a 16.9% decreased risk of all-cause mortality among ischemic stroke patients.

synapsesocial.com/papers/6a1ea94de5c5a32e9d9a6d83 https://doi.org/10.1186/s12889-025-25066-0

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October 31, 2025BMC Public HealthOpen Access

Bidirectional effect modification of greenness exposure and air pollution on ischemic stroke mortality across different temporal scales

View Full Paper

Ask AI

Bookmark

Key result

Higher residential greenness linked to ~17% lower all-cause mortality after ischemic stroke.

16.9% decreased risk
n=249,537

Why the study?

Does greenness exposure reduce mortality in ischemic stroke patients?

Population

249,537 ischemic stroke (IS) patients from Shandong Province, China (2013-2019)

Comparison

Greenness exposure vs Lower levels of greenness exposure

Design

Cohort

Follow-up

2013-2019

Authors

BZBingyin ZhangYuncheng University QCQiyong CaoBengbu Medical College QZQiongqi ZhangBengbu Medical College

Discussion

Member takes

Implication

Greenness exposure significantly reduces all-cause, cardiovascular, and stroke mortality in ischemic stroke patients, with enhanced protective effects in areas with high air pollution.

Study Design

Type

Cohort (n=249,537)

Structured PICO

Does greenness exposure reduce mortality in ischemic stroke patients?

Population

249,537 ischemic stroke patients from Shandong Province, China, evaluated between 2013 and 2019 to assess the association between greenness exposure and mortality.

Exposure

Greenness exposure (cumulative and contemporaneous NDVI/EVI)

Comparator

Lower levels of greenness exposure

Outcome

All-cause, cardiovascular, and stroke mortalityhard clinical

Main Result

Effect estimate: 16.9% decreased risk

Greenness exposure significantly reduces all-cause, cardiovascular, and stroke mortality in ischemic stroke patients, with enhanced protective effects in areas with high air pollution.

Limitations

spatial resolution variability in exposure assessments

Cite This Study

synapsesocial.com/papers/6a1ea94de5c5a32e9d9a6d83 https://doi.org/10.1186/s12889-025-25066-0

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