Feasibility of Adequate Thrombolytic Therapy with Streptokinase in Peripheral Arterial Occlusions: I. Clinical and Arteriographic Results

Convincing evidence of the efficacy of thrombolytic agents in man is scanty, although numerous studies related to this problem have been published during the last three years. Attracted by the fascinating work of Johnson on induced lysis of experimental thrombi in animals (Johnson and Tillett, 1952) and in man (Johnson and McCarty, 1959), we decided to embark on a con- trolled study of thrombolytic therapy in peripheral arteries occluded by spontaneous thrombi.