Intraindividual variability in physiological measures over time can be substantial and systematic, rather than just measurement error.
Substantial intraindividual physiological variability may confound single assessments; hypothesis-generating for repeated-measures designs in cardiovascular research.
Intraindividual differences over a four‐month period in a number of physiological variables for three subjects are examined. Autocorrelation techniques revealed the presence of systematic changes (cycles and trends). It is concluded that intraindividual differences in these variables may be nearly as large as interindividual differences and that they cannot be explained merely as errors of measurement. Possible sources of variability are discussed.
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Wieland et al. (1970) studied this question.
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