Key result
The pericardium limits right ventricular diastolic expansion during left ventricular stress, keeping pulmonary pressures lower and protecting against ventriculo-atrial regurgitation.
The pericardium plays a key physiological role in limiting right ventricular expansion during left ventricular stress, thereby protecting against excessive pulmonary pressures and ventriculo-atrial regurgitation.
Highlights pericardial constraint during LV stress; extends biventricular models but leaves clinical translation open.
The influence of the pericardium on cardiovascular phenomena has been examined and evaluated in the light of both ventricular function (modified Starling) curves and pressure-volume relationship of the pericardium. When the left ventricle is stressed, as by an increased aortic resistance, it dilates. The resulting pericardial tension limits right ventricular diastolic expansion and right ventricular work. By this mechanism pulmonary blood volume and pressures are kept at lower levels than would otherwise be present. The pericardium also protects against ventriculo-atrial regurgitation which may account for the observed descending limb of the classically conceived Starling curve.
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Berglund et al. (1955) conducted a review in Ventricular function. Pericardium influence was evaluated. The pericardium limits right ventricular diastolic expansion during left ventricular stress, keeping pulmonary pressures lower and protecting against ventriculo-atrial regurgitation.
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