⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

March 31, 2023Open Access

Supplementary Data from CD8+ Enriched “Young” Tumor Infiltrating Lymphocytes Can Mediate Regression of Metastatic Melanoma

Mark E. Dudley Colin Gross Michelle M. Langhan Marcos Ríos García Richard M. Sherry James C. Yang Giao Q. Phan Udai S. Kammula Marybeth S. Hughes Deborah E. Citrin Nicholas P. Restifo John R. Wunderlich Peter A. Prieto Jenny J. Hong Russell C. Langan Daniel Zlott Kathleen E. Morton Donald E. White Carolyn M. Laurençot Steven A. Rosenberg

View Full Paper

Ask AI

Bookmark

Share

Key Points

To investigate the role of CD8+ enriched tumor infiltrating lymphocytes in the regression of metastatic melanoma.
Provided supplementary figures and tables detailing experimental data.
Evidence indicates that CD8+ T lymphocytes contribute to tumor regression in melanoma.
Supplementary data highlights immune response mechanisms involved.

No abstract yet

We only have this paper's title and publication details.

Read it at the source→

Implication

Supplementary data shows CD8+ enriched tumor infiltrating lymphocytes can mediate regression in melanoma, suggesting a potential therapeutic target.

Abstract

Supplementary Figure S1; Supplementary Table S1.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Dudley et al. (2023) studied this question.

synapsesocial.com/papers/6a1ee2149b0150f5fd88c0a3 https://doi.org/10.1158/1078-0432.22442954

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Figure 2 from Melanoma Clonal Heterogeneity Leads to Secondary Resistance after Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes2024
2Supplementary Figure 2 from Melanoma Clonal Heterogeneity Leads to Secondary Resistance after Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes2024
3Supplementary Figure 3 from Melanoma Clonal Heterogeneity Leads to Secondary Resistance after Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes2024
4Supplementary Data 1 from Uncoupling CD4<sup>+</sup> TIL-mediated tumor killing from JAK-signaling in melanoma2024
5Supplementary Data 1 from Uncoupling CD4<sup>+</sup> TIL-mediated tumor killing from JAK-signaling in melanoma2024

Supplementary Figure 8 from CD8-Targeted IL2 Unleashes Tumor-Specific Immunity in Human Cancer Tissue by Reviving the Dysfunctional T-cell Pool2024
Supplementary Figure 8 from CD8-Targeted IL2 Unleashes Tumor-Specific Immunity in Human Cancer Tissue by Reviving the Dysfunctional T-cell Pool2024
Supplemental Data S1 from Tumor-Localized Interleukin-2 and Interleukin-12 Combine with Radiation Therapy to Safely Potentiate Regression of Advanced Malignant Melanoma in Pet Dogs2024