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Stimuli-responsive microgels, smart polymeric particles at a micro- to sub-micro scale that are capable of undergoing reversible changes in response to external triggers, have emerged as versatile tools in the field of biomedical research. The review begins by emphasizing the importance of precise control over microgel properties, such as size, composition, and responsiveness, to harness their full potential. It delves into various synthetic methodologies, including precipitation polymerization, emulsion polymerization, and microfluidic techniques. The versatility of microgels, combined with their ability to respond to specific stimuli, holds great promise for tailored biomedical applications. By dissecting the responsive attributes of microgels and unraveling the intricate structure-property relationships they embody, this review elucidates the invaluable contributions of these remarkable smart materials to diverse biomedical applications, paving the way for future advancements in the field.
Zhang et al. (Wed,) studied this question.