Key result
Point-of-care anticoagulation testing in neuroendovascular procedures lacks standard target ranges and varies across devices.
Point-of-care testing enables rapid dose titration of heparin and antiplatelet agents during neuroendovascular procedures, though physician knowledge of device differences remains limited.
Device variability requires cautious point-of-care interpretation in neuroendovascular procedures; leaves open standardization of target ranges.
POC testing is defined as diagnostic testing at or near the site of patient care. Rapid measurement of the intensity of anticoagulation and, more recently, platelet inhibition allows dose titration of adjuvant medications such a heparin and antiplatelet agents during neuroendovascular procedures. However, knowledge among practicing physicians regarding the pathophysiologic basis of these measurements and variations in knowledge about the differences among devices is often limited. This review discusses the role of anticoagulation in endovascular procedures and the currently available POC tests for anticoagulation monitoring.
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Hussein et al. (2011) conducted a review in Neuroendovascular procedures requiring anticoagulation. Point-of-care testing for anticoagulation monitoring was evaluated. Point-of-care testing for anticoagulation monitoring during neuroendovascular procedures lacks standardized target ranges and varies significantly across different devices and activators.
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