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March 1, 1989British Journal Of Nutrition353 citationsOpen Access

Assessment of adipose tissue distribution by computed axial tomography in obese women: association with body density and anthropometric measurements

MFMario FerlandJDJean‐Pierre DesprésATAngelo Tremblay

Key Result

Total adipose tissue volume computed from three CAT scans was highly correlated with body fat mass (r 0.94, P < 0.001) in premenopausal obese women.

Key Points

  • To evaluate adipose tissue distribution using computed axial tomography and examine its relationships with body density and anthropometric measurements in obese women.
  • Assessed 51 obese premenopausal women (mean age 35.7 [SD 5.5] years, mean body fat 45.9% [SD 5.6]).
  • Performed computed axial tomography (CAT) scans across three anatomical levels: lower chest, abdomen, and mid-thigh.
  • Measured body density and multiple anthropometric parameters, including waist-to-hip circumference ratio (WHR) and skinfold thicknesses.
  • Total adipose tissue volume calculated from three-site CAT scans was strongly correlated with body fat mass (r = 0.94, P < 0.001).
  • Proportion of deep abdominal fat correlated moderately with waist-to-hip ratio (r = 0.49, P < 0.001) but not with total body fat mass, whereas absolute deep abdominal fat strongly correlated with total fat mass (r = 0.72, P < 0.001).
  • Subscapular and abdominal skinfolds showed the highest correlations with both relative (r = 0.38, P < 0.01) and absolute deep abdominal fat (r = 0.65, P < 0.001 for both).

Study Design

Type

Cross-Sectional (n=51)

Multicenter

No

Structured PICO

Does computed axial tomography accurately assess body fat mass and deep abdominal fat compared to anthropometric measurements in obese women?

P
Population
51 premenopausal obese women, aged 23 to 50 years and free of cardiovascular disease or diabetes, underwent computed axial tomography and anthropometric measurements to assess adipose tissue distribution.
E
Exposure
Computed axial tomography (CAT) scans at lower chest, abdomen, and mid-thigh, and anthropometric measurements
O
Outcome
Correlation between CAT-derived adipose tissue volume/distribution and body fat mass/anthropometric measurementssurrogate

A three-site CAT-scan procedure can accurately estimate body fat mass, and absolute deep abdominal fat can be predicted from anthropometric measurements in premenopausal obese women.

Main Result

Effect estimate: r 0.94

p-value: p=<0.001

Limitations

  • Study population restricted to premenopausal obese women, limiting generalizability to men, postmenopausal women, or non-obese individuals
  • CAT involves irradiation and high cost, limiting its widespread use in large epidemiological studies

Abstract

Abdominal obesity is associated with numerous metabolic complications. Deep abdominal adipose tissue is critical in the association between the level of abdominal obesity and cardiovascular risk factors. 2. Adipose tissue localization was assessed by computed axial tomography (CAT), and its association with body density and anthropometric measurements was investigated in a sample of fifty-one obese women (percentage body fat 45.9 (SD 5.6)) aged 35.7 (SD 5.5) years. The CAT scans were performed at three levels: lower chest, abdomen and mid-thigh. 3. The total adipose tissue volume computed from these three scans was highly correlated with body fat mass (r 0.94, P less than 0.001). The proportion of deep abdominal fat as measured by the ratio of deep: total adipose tissue areas at the abdominal level was not significantly correlated with body fat mass, but it was moderately associated with the ratio of waist: hip circumferences (WHR) (r 0.49, P less than 0.001). The absolute amount of deep abdominal fat was, however, significantly correlated with body fat mass (r 0.72, P less than 0.001). 4. The subscapular (r 0.38) and the abdominal (r 0.38) skinfolds were the only two skinfolds that were significantly associated with the proportion of deep abdominal fat (P less than 0.01). These skinfolds were also those which showed the highest correlation with the absolute amount of deep abdominal fat (r 0.65, P less than 0.001, for both skinfolds). 5. A three-site CAT-scan procedure can be used for the estimation of body fat mass in premenopausal obese women. 6. In these obese women, there was no significant association between total adiposity and the proportion of deep adipose tissue at the abdominal level. 7. In premenopausal obese women, the absolute amount of deep abdominal fat can be predicted from anthropometric measurements with more accuracy than the relative amount of deep abdominal fat.

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Cite This Study

Ferland et al. (1989) conducted a cross-sectional in Obesity (n=51). Computed axial tomography (CAT) and anthropometric measurements was evaluated on Correlation between total adipose tissue volume from three CAT scans and body fat mass (r 0.94, p=<0.001). Total adipose tissue volume computed from three CAT scans was highly correlated with body fat mass (r 0.94, P < 0.001) in premenopausal obese women.

synapsesocial.com/papers/6a1f1a4b01ac3910975526d6https://doi.org/10.1079/bjn19890104
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