Key result
Renin progenitors participate in tissue morphogenesis, repair, and regeneration, and may integrate immune and endocrine responses beyond their traditional role in blood pressure homeostasis.
Renin progenitors and their descendants possess plasticity and functions beyond blood pressure regulation, including roles in tissue repair, hematopoiesis, and nephrovascular development.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for renin progenitor-targeted regeneration; prospective studies needed before clinical consideration.
Renin progenitors appear early and are found in multiple tissues throughout the embryo. Besides their well known role in blood pressure and fluid homeostasis, renin progenitors participate in tissue morphogenesis, repair, and regeneration, and may integrate immune and endocrine responses. In the bone marrow, renin cells offer clues to understand normal and neoplastic hematopoiesis.
No takes yet. Share an insight, caveat, or question.
Gómez et al. (2015) conducted a review in Renin cell biology and homeostasis. Renin progenitors participate in tissue morphogenesis, repair, and regeneration, and may integrate immune and endocrine responses beyond their traditional role in blood pressure homeostasis.
Synapse has enriched 10 related papers. Consider them for comparative context: