Key result
Normal women demonstrated 26.5% greater coronary flow, 19.6% higher myocardial oxygen consumption, and 35% lower coronary vascular resistance compared to normal men.
Why the study?
Are there differences in coronary and systemic hemodynamics between normal men and women?
Population
30 normal adults (15 men and 15 women)
Design
Cross-sectional
Authors
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Sex differences in coronary flow may inform reference values; leaves open their impact on CAD outcomes and mechanisms.
Cross-Sectional (n=30)
Are there differences in coronary and systemic hemodynamics between normal men and women?
Effect estimate: 26.5% greater coronary flow, 19.6% more oxygen consumption, 35% less coronary vascular resistance
Normal women have significantly higher baseline coronary blood flow and myocardial oxygen consumption per unit of myocardium compared to normal men, which is partly explained by differences in heart weight and hematocrit.
Rowe et al. (1959) conducted a cross-sectional in Healthy (n=30). Female sex vs. Male sex was evaluated on Coronary flow, oxygen consumption, and coronary vascular resistance (26.5% greater coronary flow, 19.6% more oxygen consumption, 35% less coronary vascular resistance). Normal women demonstrated 26.5% greater coronary flow, 19.6% higher myocardial oxygen consumption, and 35% lower coronary vascular resistance compared to normal men.
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