Key result
Methylphenidate fully blocked effort-induced depletion of regulatory control compared to placebo in healthy volunteers.
Why the study?
Does methylphenidate prevent effort-induced depletion of regulatory control in healthy volunteers?
Population
Healthy volunteers
Comparison
Methylphenidate vs Placebo
Design
RCT, double-blind
Authors
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Methylphenidate may merit testing for effort-related self-regulation deficits; extends causal RCT evidence implicating catecholamines.
RCT
Double-blind
Does methylphenidate prevent effort-induced depletion of regulatory control in healthy volunteers?
Methylphenidate prevents the depletion of regulatory control following exerted effort, implicating catecholamine systems and resting-state brain networks in self-regulation.
Sripada et al. (2014) conducted an RCT in Healthy Volunteers. Methylphenidate vs. Placebo was evaluated on Effort-induced depletion of regulatory control. Methylphenidate fully blocked effort-induced depletion of regulatory control compared to placebo in healthy volunteers.
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