Key result
Orthogonal electrical cardioversion restores sinus rhythm in 100% of refractory AF cases.
Why the study?
Standard electrical cardioversion for AF with biphasic shocks may be unsuccessful depending on various factors.
Does orthogonal electrical cardioversion restore sinus rhythm in patients with atrial fibrillation refractory to standard biphasic shocks?
Does orthogonal electrical cardioversion restore sinus rhythm in patients with atrial fibrillation refractory to standard biphasic shocks?
Orthogonal electrical cardioversion may be a safe and effective rescue strategy for atrial fibrillation refractory to standard biphasic shocks.
May rescue biphasic-refractory AF; hypothesis-generating and requires prospective validation before practice change.
Background Biphasic waveform shock has been established as the standard method for cardioversion of atrial fibrillation (AF). Depending on various factors, standard electrical cardioversion for AF may be unsuccessful in some cases, even with biphasic shocks. Case summary We report the safety and efficacy of orthogonal electrical cardioversion (OECV) as an alternative in patients with paroxysmal AF refractory to standard biphasic electrical cardioversion after up to three subsequent shocks of increasing energy and/or two or three initial shocks with maximum energy of 200-Joules. Shocks were delivered with two external defibrillators via two sets of adhesive electrode pads to apply two perpendicular electrical vectors in a simultaneous-sequential mode in antero-lateral and antero-posterior configuration. Five patients, mean age 54.4 ± 11, three with hypertensive heart disease and a body mass index 27.2 ± 2 kg/m2. All individual mean impedance before OECV was 79 ± 5 Ω with a mean peak current applied of 22 ± 4.5 A. Restoration of sinus rhythm with OECV was achieved acutely and sustained in all five patients. No patients developed haemodynamic instability or thromboembolic events. Discussion Double simultaneous shocks in an orthogonal configuration could theoretically decrease the defibrillation threshold through the ability of sequential pulses applying a more efficient and uniform current density. OECV using lower/medium energy may be another useful rescue strategy in AF refractory to standard biphasic shocks.
No takes yet. Share an insight, caveat, or question.
Velázquez‐Rodríguez et al. (2020) studied Atrial fibrillation refractory to biphasic shocks (n=5). Orthogonal electrical cardioversion (OECV) was evaluated on Restoration of sinus rhythm. Orthogonal electrical cardioversion successfully restored sinus rhythm in 100% (5/5) of patients with atrial fibrillation refractory to standard biphasic shocks.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: