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We examine the small-sample behaviour of the maximum likelihood estimator for the Poisson regression model with random covariates. Analytic expressions for the second-order bias and mean squared error are derived, and we undertake some numerical evaluations to illustrate these results for the single covariate case. The properties of the bias-adjusted maximum likelihood estimator are investigated in a Monte Carlo experiment. Correcting the estimator for its second-order bias is found to be effective in the cases considered, and we recommend its use when the Poisson regression model is estimated by maximum likelihood with small samples.
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Chen et al. (2010) studied this question.
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