Key result
Type 2 diabetes was associated with a lack of significant improvement in overall heart rate variability (SDNN) after 8 weeks of cardiac rehabilitation compared to patients without diabetes.
Why the study?
Does an 8-week cardiac rehabilitation program improve heart rate variability indices differently in CAD patients with versus without type 2 diabetes?
Cohort (n=141)
No
Does an 8-week cardiac rehabilitation program improve heart rate variability indices differently in CAD patients with versus without type 2 diabetes?
An 8-week cardiac rehabilitation program improves exercise capacity in all CAD patients, but is less effective at improving autonomic function (HRV) in those with concurrent type 2 diabetes.
METHOD: The study population included 141 male CAD patients prospectively and consecutively admitted to an outpatient comprehensive CR program. Twenty-seven patients with type-2 diabetes were compared with 114 males without diabetes. The participants performed a 45-min cycle ergometer interval training alternating 4-min workload and a 2-min active restitution three times a week for 8 weeks. The training intensity was adjusted so that the patient's heart rate achieved the training heart rate calculated according to the Karvonen formula. At the baseline and after 8 weeks, all the patients underwent the HRV assessment. RESULTS: HRV indices in the patients with diabetes were significantly lower as compared to the patients without diabetes in SDNN, TP, LF parameters, both at the baseline and after 8 weeks of CR. After 8 weeks of CR, a significant improvement of TP, SDNN, pNN50% and HF occurred in the patients without diabetes, whereas in the patients with diabetes only HF component improved significantly. CONCLUSIONS: As regards HRV indices, CR seems to be less effective in patients with CAD and type-2 diabetes.
No takes yet. Share an insight, caveat, or question.
Szmigielska et al. (2021) conducted a cohort in Coronary artery disease (n=141). Type 2 diabetes vs. No diabetes was evaluated on Heart rate variability (SDNN) after 8 weeks of cardiac rehabilitation (p=0.33 (within T2DM group), 0.03 (within non-DM group)). Type 2 diabetes was associated with a lack of significant improvement in overall heart rate variability (SDNN) after 8 weeks of cardiac rehabilitation compared to patients without diabetes.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: