Two quinoline alkaloids, japonine (1) and eduline (2) were isolated from the methanol extract of the leaves of Orixa japonica as relaxants against rat small intestine muscle. The activity of these alkaloids was comparable to that of the typical muscle relaxant papaverine (4). This is also the first report of the isolation of eduline (2) from O. japonica.
No takes yet. Share an insight, caveat, or question.
Funayama et al. (2001) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: