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October 1, 1967Cardiovascular Research205 citations

Measurement of the Angina Threshold Using Atrial Pacing: A New Technique for the Study of Angina Pectoris

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GSG.E. SowtonGuy's HospitalRBR BalconMinisterio de Salud PúblicaDCDavid F. CrossRutland Regional Medical Center

Key Result

Atrial pacing identified a tension-time index threshold above which angina occurs, with exceptions in some patients explained by an abnormal increase in heart size at higher heart rates.

Key Points

  • The research aims to identify the threshold level of tension-time index that triggers angina pectoris.
  • Utilized atrial pacing to induce conditions for measuring angina threshold.
  • Analyzed end-diastolic x-ray films for heart size changes during increased rates.
  • Identified a tension-time index threshold above which angina occurs in patients.
  • Observed an unexpected increase in heart size with increasing pacing rate.

Structured PICO

Can atrial pacing be used to measure the tension-time index threshold for angina in patients with angina pectoris?

P
Population
Patients with angina pectoris
I
Intervention
Atrial pacing
O
Outcome
Tension-time index threshold for anginasurrogate

Atrial pacing is a novel technique that can identify a tension-time index threshold for the onset of angina pectoris.

Abstract

A threshold level of tension-time index has been found in patients with angina pectoris above which angina occurred. End-diastolic x-ray films showing an increase, rather than the usual decrease, in heart size with increasing rate were thought to explain the absence of a threshold level in some patients.

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Cite This Study

Sowton et al. (1967) studied this question. Atrial pacing identified a tension-time index threshold above which angina occurs, with exceptions in some patients explained by an abnormal increase in heart size at higher heart rates.

synapsesocial.com/papers/6a1fac4ae47f012c480757bahttps://doi.org/10.1093/cvr/1.4.301
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1HAeMODYNAMIC CONSEQUENCES OF CORONARY HEART DISEASE WITH OBSERVATIONS DURING ANGINAL PAIN AND ON THE EFFECT OF NITROGLYCERINE1958 · 201 citations
  2. 2Effects of Changing Heart Rate in Man by Electrical Stimulation of the Right Atrium1965 · 258 citations
  3. 3The George Fahr Lecture1952 · 170 citations
  4. 4Relation of Heart Rate and Systolic Blood Pressure to the Onset of Pain in Angina Pectoris1967 · 571 citations
  5. 5Hemodynamic Studies during Angina Pectoris1965 · 105 citations