Key result
Breathing 100% oxygen produced no significant haemodynamic benefit during exercise-induced angina pectoris, although it reduced heart rate and cardiac index at rest.
Why the study?
Does breathing 100% oxygen improve haemodynamics during exercise-induced angina pectoris in male patients with coronary heart disease?
Does breathing 100% oxygen improve haemodynamics during exercise-induced angina pectoris in male patients with coronary heart disease?
Breathing 100% oxygen does not provide haemodynamic benefits during exercise-induced angina in patients with coronary heart disease, contrasting with its effects in pacing-induced angina.
No haemodynamic benefit from 100% oxygen in exercise angina warrants clinical caution; leaves open rest effects and contrasts with pacing-induced models.
Lecerof, H. (1974).Thorax, 29, 673-677. Central haemodynamics during oxygen breathing in angina pectoris. The haemodynamic effects of breathing 100% oxygen have been studied by right heart catheterization at rest and during bicycle exercise in nine male patients with coronary heart disease. Oxygen breathing produced no significant haemodynamic benefit during angina pectoris induced by physical exercise, although at rest a reduction in heart rate and cardiac index was evident. The favourable effects of 100% oxygen breathing described in pacing-induced angina pectoris cannot therefore be transferred to exercise-induced angina probably because the myocardial blood flow during the latter condition is hampered by an increased left ventricular end-diastolic pressure.
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H. Lecerof (1974) studied coronary heart disease with angina pectoris (n=9). 100% oxygen breathing was evaluated on haemodynamic effects. Breathing 100% oxygen produced no significant haemodynamic benefit during exercise-induced angina pectoris, although it reduced heart rate and cardiac index at rest.
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