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June 1, 2026Natural Product Research

Phytosterols from Lagenaria siceraria as novel bioactive compounds for the management of inflammatory and oxidative stress conditions: an in vitro and in silico approach

B Harshitha Mubarakali D Satheesh Babu N Fazeela Mahaboob Begum S.M

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Key Points

This research aims to investigate the potential of phytosterols from Lagenaria siceraria for managing inflammatory and oxidative stress conditions.
In vitro assays to evaluate the effects of phytosterols on inflammation and oxidative stress.
In silico analyses to predict the bioactivity of these compounds.
Phytosterols significantly reduce markers of inflammation in vitro.
Compounds demonstrate potential antioxidant activity, indicating effectiveness against oxidative stress.

Implication

In vitro and in silico approaches reveal phytosterols may treat inflammation and oxidative stress conditions, suggesting new therapeutic strategies.

Abstract

seeds might be used for the treatment of inflammatory and oxidative stress as novel therapeutic strategies.

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Cite This Study

Harshitha et al. (2026) studied this question.

synapsesocial.com/papers/6a1fc47adee9eb8c0dce5fd7 https://doi.org/10.1080/14786419.2026.2680086

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