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June 3, 2026Journal of Cardiovascular Imaging0 citationsOpen Access

Clinical associations of right ventricular strain in community-acquired pneumonia: a prospective cohort study

EBEren Ozan BakirIzmir UniversityMGMutlu Onur GüçsavIzmir UniversityABAhmet Anil BaskurtIzmir University

Key Points

  • This study aims to determine the clinical significance of right ventricular strain in patients with community-acquired pneumonia.
  • Prospective cohort design involving 80 hospitalized pneumonia patients.
  • Echocardiographic assessment including measurement of right ventricular global longitudinal strain (RVGLS).
  • Comparison of clinical and echocardiographic data between reduced and normal RVGLS groups.
  • Reduced RVGLS was observed in 28 patients (35%); these patients had higher NT-proBNP and troponin levels.
  • Significantly longer hospitalization durations (>7 days: 50.0% vs. 28.8%, P=0.044; >10 days: 21.4% vs. 5.8%, P=0.029) and increased oxygen therapy duration (4.30 days vs. 2.60 days, P=0.043) were noted.
  • No significant difference in ICU admission or short-term mortality between reduced and normal RVGLS patients.

Abstract

Abstract Background Pneumonia remains a major cause of morbidity and mortality worldwide, and right ventricular dysfunction may contribute to adverse clinical outcomes. Right ventricular global longitudinal strain (RVGLS) is an emerging echocardiographic marker for assessing right ventricular function, but its prognostic and clinical utility in pneumonia has not been fully clarified. Methods Eighty patients hospitalized with pneumonia underwent echocardiographic assessment, including RVGLS measurement via 2D speckle tracking echocardiography. Patients were categorized into two groups: reduced RVGLS (absolute value 7 days (50.0% vs. 28.8%, P = 0.044) and > 10 days (21.4% vs. 5.8%, P = 0.029), as well as longer duration of oxygen therapy (4.30 days vs. 2.60 days, P = 0.043), were significantly more common in the reduced RVGLS group. Intensive care unit admission and short-term mortality did not differ significantly between groups. Conclusions Reduced RVGLS in pneumonia patients is associated with markers of disease severity, longer hospital stays, and extended oxygen therapy requirements, even without overt right ventricular failure. RVGLS assessment may assist in identifying patients at risk for a complicated clinical course.

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Cite This Study

Bakir et al. (2026) studied this question.

synapsesocial.com/papers/6a1fc47adee9eb8c0dce6042https://doi.org/10.1186/s44348-026-00074-9
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