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Investigates genetic variants affecting Dupuytren's contracture susceptibility, suggesting new predictive approaches.
PURPOSE: Dupuytren's contracture (DC) is a common fibroproliferative disorder with strong genetic predisposition. This study aimed to investigate the association between genetic variants in key fibrotic pathways and DC susceptibility in a Lithuanian population. MATERIALS AND METHODS: rs1668347. No significant associations were found for the other investigated SNPs. CONCLUSIONS: rs1668347 provide additional insights into the genetic basis of DC and may contribute to the development of predictive tools and targeted therapies for this debilitating condition.
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Vilkeviciute-Petraite et al. (2026) studied this question.
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