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June 3, 20260 citationsOpen Access

Utility of the Agatston Score in Detecting Obstructive Coronary Artery Disease: A Case Report on the Limitations of Lipid-Based Risk Stratification

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DMDr. N. MurugesanITPEnergised Group (India)DADr. Mark Christopher ArokiarajITPEnergised Group (India)VMVenkatram MurugesanITPEnergised Group (India)

Key Result

Coronary Artery Calcium (CAC) scoring identified high-grade stenosis requiring stenting in a 72-year-old male with normal lipid parameters, underscoring its utility as a diagnostic tool.

Key Points

  • This report assesses the effectiveness of the Agatston score in identifying obstructive coronary artery disease, particularly in patients with normal lipid levels.
  • Case report of a 72-year-old male with a history of myocardial infarction presenting with normal lipid parameters and a CAC score over 1000.
  • Diagnostic procedures included Coronary Angiogram (CAG) and stenting for identified high-grade stenosis.
  • Discovery of high-grade stenosis despite normal lipid levels highlights limitations of traditional lipid-based risk assessment.
  • Successful intervention via CAG and stenting underscores the importance of non-invasive calcium scoring.

Study Design

Type

Case Report (n=1)

Structured PICO

P
Population
A 72-year-old male with a history of myocardial infarction and normal lipid parameters who presented with a Coronary Artery Calcium score exceeding 1000.
E
Exposure
Coronary Artery Calcium (CAC) scoring followed by Coronary Angiogram (CAG) and stenting
O
Outcome
Detection of high-grade stenosis

CAC scoring can identify critical obstructive coronary artery disease in high-risk patients who have normal lipid parameters.

Abstract

Abstract: - Traditional cardiovascular risk assessment often relies heavily on lipid panels and symptomatic presentation. However, a significant cohort of patients remains at risk despite maintaining "normal" cholesterol levels. This case report discusses a 72-year-old male with a history of myocardial infarction (2019) who presented with a paradoxical profile: stable, normal lipid parameters but a critical Coronary Artery Calcium (CAC) score exceeding 1000. The subsequent discovery of high-grade stenosis and successful intervention via Coronary Angiogram (CAG) and stenting underscores the necessity of non-invasive calcium scoring. This report argues for the broader integration of CAC scoring as a regular diagnostic tool, not only for the elderly but as a proactive screening measure for younger adults to intercept early-stage atherosclerosis.

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Cite This Study

Murugesan et al. (2026) conducted a case report in Obstructive Coronary Artery Disease (n=1). Coronary Artery Calcium (CAC) scoring was evaluated on Detection of high-grade stenosis. Coronary Artery Calcium (CAC) scoring identified high-grade stenosis requiring stenting in a 72-year-old male with normal lipid parameters, underscoring its utility as a diagnostic tool.

synapsesocial.com/papers/6a1fc58bdee9eb8c0dce6fe9https://doi.org/10.5281/zenodo.20486297
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