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June 3, 2026Open Access

Long-term outcomes of regenerative periodontal therapy and orthodontic treatment: 20-year results from a prospective study.

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Authors

ARAndrea RoccuzzoYLYuan LiGSGiovanni E. Salvi

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Overview

Prospective study evaluates clinical outcomes of combined periodontal and orthodontic treatments in severely compromised teeth, suggesting effective long-term tooth preservation.

Key Points

  • Evaluate the 20-year clinical outcomes of periodontal regenerative and orthodontic treatment for severely compromised teeth.
  • Prospective study with 48 patients having Stage IV periodontitis and test teeth with probing depth ≥ 7 mm.
  • Treatment protocol included instrumentation, regenerative surgery using EMD, orthodontic treatment, and supportive care.
  • Clinical parameters recorded at baseline, 10-year, and 20-year follow-ups.
  • Tooth survival at 20 years was 89.1% (CI: 79.4-99.9%), with a complication-free probability of 86.3% (CI: 75.7-98.3%).
  • Full-mouth plaque scores decreased from 48.8% to 14.6% (p < 0.001), and bleeding scores from 55.5% to 10.2% (p < 0.001).
  • Mean probing depth decreased from 6.3 mm to 3.0 mm (p < 0.001), with 81.8% of cases achieving treatment success.

Cite This Study

Roccuzzo et al. (2026) studied this question.

synapsesocial.com/papers/6a1fc5d7dee9eb8c0dce7294https://doi.org/10.48620/98282
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