Why the study?
Does rheumatoid arthritis increase carotid intima media thickness compared to healthy controls?
Population
360 participants without known cardiovascular disease, comprising 243 patients with Rheumatoid Arthritis and…
Comparison
Rheumatoid arthritis vs Healthy controls without rheumatoid arthritis
Design
Cross-sectional
Key result
Rheumatoid arthritis was not associated with increased carotid intima media thickness compared to healthy controls (0.556 mm vs 0.573 mm, p=0.220).
Authors
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Similar cIMT in well-treated low-activity RA driven by age and hypertension; leaves open whether disease activity modulates broader CV risk.
Cross-Sectional (n=360)
No
Does rheumatoid arthritis increase carotid intima media thickness compared to healthy controls?
Mean Difference: 0.017 (95% CI -0.01–0.045)
Absolute Event Rate: 0.556% vs 0.573%
p-value: p=0.220
In well-treated rheumatoid arthritis patients with low disease activity, carotid intima media thickness is similar to healthy controls and is primarily driven by traditional cardiovascular risk factors like age and hypertension.
Stoep et al. (2015) conducted a cross-sectional in Rheumatoid arthritis (n=360). Rheumatoid arthritis vs. Healthy controls without RA was evaluated on Carotid intima media thickness (cIMT) (MD 0.017, 95% CI -0.010-0.045, p=0.220). Rheumatoid arthritis was not associated with increased carotid intima media thickness compared to healthy controls (0.556 mm vs 0.573 mm, p=0.220).