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October 31, 2011Journal of Medicinal ChemistryOpen Access

Optimization of a Potent Class of Arylamide Colony-Stimulating Factor-1 Receptor Inhibitors Leading to Anti-inflammatory Clinical Candidate 4-Cyano-N-2-(1-cyclohexen-1-yl)-4-[1-[(dimethylamino)acetyl-4-piperidinyl]phenyl]-1H-imidazole-2-carboxamide (JNJ-28312141)

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Authors

CICarl R. IlligJohnson & Johnson (United States)CMCarl L. MantheyJanssen (United States)MWMark J. WallUniversity of Warwick

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Illig et al. (2011) studied this question.

synapsesocial.com/papers/6a1fc76b76b663ca04df625dhttps://doi.org/10.1021/jm200900q
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