A mechanically compliant MnO 2 –MXene–GelMA cardiac patch for modulating the post-infarction microelectrical environment and alleviating oxidative stress | Synapse
June 3, 2026Open Access
A mechanically compliant MnO 2 –MXene–GelMA cardiac patch for modulating the post-infarction microelectrical environment and alleviating oxidative stress
Key Points
This research aims to develop a cardiac patch using MnO2–MXene–GelMA to improve post-infarction outcomes by modulating microelectrical conditions and reducing oxidative stress.
Developed a 3D-printable MnO2–MXene–GelMA cardiac patch.
Evaluated its mechanical compliance and electrical coupling in a cardiac context.
Assessed the ROS scavenging capability to alleviate oxidative stress.
The patch enhanced electrical coupling in cardiac tissue leading to improved microelectrical signals.
Significantly reduced oxidative stress markers compared to control conditions, indicating effective ROS scavenging.
Abstract
A 3D-printable MnO 2 –MXene–GelMA cardiac patch with mechanical compliance, electrical coupling, and ROS scavenging for post-infarction microelectrical modulating and oxidative stress alleviation.