ABSTRACT In this study, Raspberry ketone is synthesized from phenol and 4‐hydroxy‐2‐butanone using metal‐exchanged bentonite catalysts. Catalysts such as Al/bentonite, Fe/bentonite, Zn/bentonite, and Zr/bentonite were utilized, where Al/bentonite exhibited the highest conversion of 4‐hydroxy‐2‐butanone, 99% with 70% selectivity for Raspberry ketone. The excellent activity was observed due to the high acidity of Al/bentonite compared to the other metal‐exchanged catalysts. Different reaction parameters, such as temperature, time, molar ratio, and catalyst reusability, were studied. The catalyst characterization was performed using XPS, N2‐adsorption–desorption, and FTIR analysis. The use of a heterogeneous catalyst provides a cost‐effective and environmentally friendly approach to the production of raspberry ketone.
Patange et al. (Mon,) studied this question.