Key result
Higher HbA1c was associated with a statistically significant increase in 72-hour mortality in diabetic patients with acute ischemic stroke (p=0.0002).
Why the study?
Diabetes prevalence is rapidly increasing globally, but the correlation between HbA1c and short-term mortality in diabetic patients hospitalized with acute macrovascular complications required study.
Is higher HbA1c associated with increased 72-hour mortality in diabetic patients admitted with acute macrovascular complications?
Observational
No
Is higher HbA1c associated with increased 72-hour mortality in diabetic patients admitted with acute macrovascular complications?
p-value: p=0.0002
Higher HbA1c levels at admission are associated with increased short-term (72-hour) mortality in diabetic patients presenting with acute ischemic stroke.
May aid early risk stratification in diabetic stroke; leaves open whether glycemic intervention improves 72-hour survival.
Introduction: Diabetes is a global endemic with rapidly increasing prevalence in both developing and developed countries. Over the past two decades the prevalence of diabetes has risen from an estimated 30 million cases in 1985 to 415 million in 2017. Aims & objectives: To study HbA1c and other biochemical & clinical parameters of acute ischemic cerebrovascular accident, acute coronary syndrome and acute limb ischemia in diabetic patients. Specific objectives: · To estimate 72 hrs mortality in hospitalized patient with diabetes mellitus with acute ischemic cerebrovascular accident. · To estimate 72 hrs mortality in hospitalized patient with diabetes mellitus with acute coronary syndrome · To estimate 72 hrs mortality in hospitalized patient with diabetes mellitus with acute limb ischemia · To study correlation between HbA1C and 72 hours mortality of patients with acute macrovascular events among diabetics. Materials & methods: Department of general medicine, R.G.Kar Medical College and Hospital.Cases were selected from medicine inpatients department of R.G.Kar Medical College and Hospital. 1st July, 2018-30th June 2019. This is an observational prospective study Conclusion: In our study we found that higher HbA1C is associated with statistically signicant increase in 72 hour mortality in patients with acute ischemic stroke and trend of increased mortality (though not statistically signicant) in patients (p=0.0002 & 0.056 respectively)
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Mukherjee et al. (2021) conducted an observational in Diabetes mellitus with acute macrovascular complications. Higher HbA1c vs. Lower HbA1c was evaluated on 72-hour mortality (p=0.0002). Higher HbA1c was associated with a statistically significant increase in 72-hour mortality in diabetic patients with acute ischemic stroke (p=0.0002).
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