Degrees of Difficulty of Water-Consuming Reactions in the Absence of Enzymes

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDegrees of Difficulty of Water-Consuming Reactions in the Absence of EnzymesRichard WolfendenView Author Information Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina 27599 Cite this: Chem. Rev. 2006, 106, 8, 3379–3396Publication Date (Web):July 13, 2006Publication History Received17 January 2006Published online13 July 2006Published inissue 1 August 2006https://pubs.acs.org/doi/10.1021/cr050311yhttps://doi.org/10.1021/cr050311yresearch-articleACS PublicationsCopyright © 2006 American Chemical SocietyRequest reuse permissionsArticle Views2250Altmetric-Citations178LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Hydrolysis,Kinetic parameters,Peptides and proteins,Phosphates,Transition states Get e-Alerts